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Interaction of insecticides with the Ca2+-pump activity of sarcoplasmic reticulum

✍ Scribed by M.C. Antunes-Madeira; Vitor M.C. Madeira

Book ID
119027157
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
502 KB
Volume
17
Category
Article
ISSN
0048-3575

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In porcine malignant hyperthermia-susceptible (MHS) skeletal muscles, calcium release is abnormal and resting calcium may be elevated. Thus MHS muscles may have prolonged twitch relaxation and lower fusion frequencies, which would be augmented by inhibition of sarcoplasmic reticulum (SR) Ca2+ adenos