✦ LIBER ✦
Interaction of epidermal growth factor with initiators and complete carcinogens in the C3H10T1/2 cell culture System
✍ Scribed by Harvey R. Herschman; David Brankow
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 367 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0730-2312
No coin nor oath required. For personal study only.
✦ Synopsis
Unlike 12-0-tetradecanoylphorbol-13-acetate, epidermal growth factor (EGF) could not promote the appearance of type 111 foci from initiated C3HIOT1/2 cells.
At appropriate concentrations, EGF induced the formation of type I1 colonies in the absence of any initiator. At higher concentrations, EGF suppressed the induction of both type I1 and type 111 colonies elicited by methylcholanthrene.