## Abstract Hexyl methacrylate (HMA), methyl methacrylate (MMA), and methacrylic acid (MAA) were used as comonomers to produce a low glass transition temperature material, potentially useful in fabricating a small diameter vascular graft. Because it has been shown that grafts seeded with endothelia
Interaction of endothelial cells with methacrylic terpolymer biomaterials
β Scribed by Daniel E. Heath; Stuart L. Cooper
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 365 KB
- Volume
- 92B
- Category
- Article
- ISSN
- 1552-4973
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A biomaterial system with tunable mechanical properties was synthesized through random copolymerization of hexyl methacrylate, methyl methacrylate, and methacrylic acid. The composition, molecular weight, water absorption, glass transition temperature, and tensile properties of the polymer system were characterized, and the biocompatibility of the material was demonstrated by the ability of human umbilical vein endothelial cells to adhere, proliferate, and spread on the polymer surface. No difference was observed in the behavior of the endothelial cells on the materials regardless of material stiffness. Β© 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010
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