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Interaction of cofilin with the serine phosphatases PP1 and PP2A in normal and neoplastic human T lymphocytes

✍ Scribed by Yvonne Samstag; Gabriele Nebl


Book ID
114098851
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
259 KB
Volume
43
Category
Article
ISSN
0065-2571

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The serine phosphatases PP1 and PP2A ass
✍ Andreas Ambach; Jochen Saunus; Mathias Konstandin; Sebastian Wesselborg; Stefan  πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 192 KB

Cofilin, an actin-depolymerizing protein, is essential for the functional dynamics of the actin cytoskeleton and for cell viability. In unstimulated human peripheral blood T lymphocytes cofilin is phosphorylated and localized in the cytoplasm. Following co-stimulation through accessory receptors (e.