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Interaction of Cardiotoxins with Membranes: A Molecular Modeling Study

โœ Scribed by Efremov, Roman G.; Volynsky, Pavel E.; Nolde, Dmitry E.; Dubovskii, Peter V.; Arseniev, Alexander S.

Book ID
118514667
Publisher
Biophysical Society
Year
2002
Tongue
English
Weight
413 KB
Volume
83
Category
Article
ISSN
0006-3495

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The action of 7.2 microM cardiotoxin on 0.25% human erythrocytes in a plasma extender solution was studied by the interaction of toxin with intact red blood cells and subsequent hemolysis of the cells. The binding of toxin to cells was completed within 10 min, whereas the membrane rigidity was weake