Interaction of branched chain polymeric polypeptides with phospholipid model membranes
✍ Scribed by I. B. Nagy; I. Haro; M. A. Alsina; F. Reig; F. Hudecz
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1998
- Tongue
- English
- Weight
- 140 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0006-3525
No coin nor oath required. For personal study only.
✦ Synopsis
The surface properties at the air/water interface and the interaction of branched chain polymeric polypeptides with a general formula poly[Lys-(DL-Ala m -X i )], where X Å M (AK), Ser (SAK), or Glu (EAK), with phospholipids were investigated. Polylysine derivatives with polycationic (SAK, AK) or amphoteric (EAK) were capable to spread and form stable monomolecular layers. The stability of monolayers at the air/water interface was dependent * Abbreviations for amino acids and their derivatives follow the revised recommendation of the IUPAC-IUB Committee on Biochemical Nomenclature, entitled ''Nomenclature and Symbolism for Amino Acids and Peptides'' (recommendations of 1983). Nomenclature of branched polypeptides is used in accordance with the recommended nomenclature of graft polymers. 23 For the sake of brevity, codes of branched polypeptides were constructed by us using the one-letter symbols of amino acids (Table ). All amino acids are of the L configuration unless otherwise stated.