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Interaction of Ap1, Ap2, and Sp1 with the Regulatory Regions of the Human Pro-α1(I) Collagen Gene

✍ Scribed by Wilma P. Vergeer; José M. Sogo; P.J. Pretorius; Wilhelmine N. de Vries


Book ID
115568167
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
433 KB
Volume
377
Category
Article
ISSN
0003-9861

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The first intron of the human Pro alpha 1(I) collagen gene contains an orientation-dependent enhancer composed of both positive and negative cis-acting elements involved in the transcriptional regulation of this gene. Deletion of a 360 bp Sau 3A intronic fragment spanning nucleotide +494 to +854 (S3