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Interaction of Aminoazoles with Meldrum′s Acid and Dialkyl Ketones or Cyclohexanone.

✍ Scribed by V. V. Lipson; V. V. Borodina; M. G. Shirobokova; S. M. Desenko; O. V. Shishkin; R. I. Zubatyuk


Book ID
102014561
Publisher
John Wiley and Sons
Year
2007
Weight
23 KB
Volume
38
Category
Article
ISSN
0931-7597

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Coumarin-3-carboxylic acids were obtained in high yields with excellent purity from ortho-hydroxybenzaldehydes and Meldrum's acid after a 2 h reflux in ethanol. The less reactive ketones were first reacted with alcoholic ammonia to form ketimines, which were then condensed with Meldrum's acid to gen