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Interaction of 1,2,3,4-Tetrahydroisoquinoline with Some Components of Cigarette Smoke: Potential Implications for Parkinson's Disease

✍ Scribed by Ramón Soto-Otero; Ricardo Riguera-Vega; Estefanı́a Méndez-Álvarez; Inés Sánchez-Sellero; Manuel López-Rivadulla Lamas

Book ID
115578506
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
54 KB
Volume
222
Category
Article
ISSN
0006-291X

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✍ Ramón Soto-Otero; Carolina Sanmartín-Suárez; Sofía Sánchez-Iglesias; Álvaro Herm 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB

## Abstract Tetrahydropapaveroline (THP) is a compound derived from dopamine monoamine oxidase–mediated metabolism, particularly present in the brain of parkinsonian patients receiving L‐dopa therapy, and is capable of causing dopaminergic neurodegeneration. The aim of this work was to evaluate the