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Interaction in the cerebral metabolism of the biogenic amines: Effect of intravenous infusion of l-tryptophan on the metabolism of dopamine and 5-hydroxyindoles in brain and cerebrospinal fluid

✍ Scribed by A. T. B. MOIR

Book ID
117956131
Publisher
Nature Publishing Group
Year
1971
Tongue
English
Weight
975 KB
Volume
43
Category
Article
ISSN
0007-1188

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Effects of pyrroxan and chlordiazepoxide
Effects of pyrroxan and chlordiazepoxide on biogenic amine metabolism in the rat brain
✍ T. A. Pugsley; W. Lippmann πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 631 KB

Pyrroxan (20 mg/kg, i.p.) , a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central e-adrenergic receptor blocking activity, in contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover.