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Interaction between the C-terminal domains of measles virus nucleoprotein and phosphoprotein: A tight complex implying one binding site

✍ Scribed by David Blocquel; Johnny Habchi; Stéphanie Costanzo; Anthony Doizy; Michael Oglesbee; Sonia Longhi


Book ID
115561347
Publisher
Cold Spring Harbor Laboratory Press
Year
2012
Tongue
English
Weight
430 KB
Volume
21
Category
Article
ISSN
0961-8368

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## Abstract The major inducible 70 kDa heat shock protein (hsp70) binds the measles virus (MeV) nucleocapsid with high affinity in an ATP‐dependent manner, stimulating viral transcription and genome replication, and profoundly influencing virulence in mouse models of brain infection. Binding is med