Fenfluramine (FE) is a halogenated amphetamine derivative that has been used in the treatment of obesity. It has been suggested that the effects of FE on the striatum are mediated by serotonergic mechanisms. However, several major afferent systems may be involved, and administration of FE may be use
Interaction between serotonergic and dopaminergic systems detected in striatum by differential pulse voltammetry
β Scribed by M.G. De Simoni; R. Giglio; G. Dal Toso; W. Kostowski; S. Algeri
- Book ID
- 115879137
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 137 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0014-2999
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Fenfluramine (FE) is a halogenated amphetamine derivative used in the treatment of obesity and thought to induce serotonin (5-HT) release from nerve terminals and to reduce re-uptake. However, other pathways may also be involved. In this work, the effects of FE on the major striatal afferent systems
## Abstract Pulse voltammetries allowed to demonstrate that interlocking of a dibenzocrown ether with the homoβ or heterodinuclear bismacrocyclic transition metal complexes leads to increased stability of the mixedβvalence state. Based on the shape of differential pulse curves, the value of comprop
The effects of growth hormone (GH) and somatomedin C (SmC), as well as those of apomorphine, dopamine (DA) agonist, or haloperidol (DA antagonist), upon the size of striatal voltammetric peaks 2 and 5 were investigated. Local intrastriatal injections of GH or SmC were followed by an increase in the