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Interaction between oleic acid-containing pH-sensitive and plain liposomes Fluorescent spectroscopy studies

✍ Scribed by V.P. Torchilin; A.N. Lukyanov; A.L. Klibanov; V.G. Omelyanenko

Book ID
115926347
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
421 KB
Volume
305
Category
Article
ISSN
0014-5793

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Temperature-dependent aggregation of pH-
Temperature-dependent aggregation of pH-sensitive phosphatidyl ethanolamine-oleic acid-cholesterol liposomes as measured by fluorescent spectroscopy
✍ V.P. Torchilin; V.G. Omelyanenko; A.N. Lukyanov πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 574 KB

pH-sensitive liposomes made of phosphatidyl ethanolamine-oleic acid-cholesterol (4:2:4 molar ratio) at neutral pH values aggregate at approximately 40 degrees C. The aggregation is accompanied by liposome destabilization and by the release of intraliposomal fluorescent marker (calcein). Both aggrega