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Interaction between Membrane Functions and Protein Synthesis in Reticulocytes: Specific Cleavage of 28-S Ribosomal RNA by a Membrane Constituent

✍ Scribed by Daniel WRESCHNER; Daniele MELLOUL; Max HERZBERG

Book ID: 115116602
Publisher: John Wiley and Sons
Year: 1978
Tongue: English
Weight: 646 KB
Volume: 85
Category: Article
ISSN: 1432-1327
DOI: 10.1111/j.1432-1033.1978.tb12231.x

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In this work we consider the differential effect of Valinomycin used at different concentrations both on the protein synthesis of reticulocytes and on 42K exchange. We demonstrate that there is a two step action of this antibiotic. At 10(-6)M and below the drug has no effect on the 42K exchange, but