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Interaction between grapefruit juice and hypnotic drugs: comparison of triazolam and quazepam

✍ Scribed by Koh-ichi Sugimoto; Nobutaka Araki; Masami Ohmori; Ken-ichi Harada; Yimin Cui; Shuichi Tsuruoka; Atsuhiro Kawaguchi; Akio Fujimura


Publisher
Springer
Year
2006
Tongue
English
Weight
154 KB
Volume
62
Category
Article
ISSN
0031-6970

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To investigate the potential interaction between selected ingredients of grapefruit juice and, the transport of talinolol, a P-gp substrate, across Caco-2 cells monolayers was determined in the absence and presence of distinct concentrations of grapefruit juice, bergamottin, 6 0 ,7 0 -dihydroxyberga