Interaction between gallocatechin gallate and caffeine in crystal structure of 1:2 and 2:2 complexes

✍ Scribed by Takashi Ishizu; Hiroyuki Tsutsumi; Takashi Sato

• Book ID: 104096579
• Publisher: Elsevier Science
• Year: 2009
• Tongue: French
• Weight: 506 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2009.04.113

✦ Synopsis

A suspension of (À)-gallocatechin gallate (GCg) and caffeine in water afforded two kinds of complexes, the 1:2 and 2:2 complexes of GCg and caffeine. The crystal structures of the two complexes were determined by X-ray crystallography. The driving force for the formation of the 1:2 and 2:2 complexes was thought to be mainly p-p interactions between the A, B 0 rings of GCg and the six-membered rings of caffeines, and those between the B ring of GCg and caffeine, the B 0 ring of GCg and caffeine, and the A rings of GCgs, respectively.