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Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: a familial study

✍ Scribed by Nichola Johnson; Olivia Fletcher; Cristina Naceur-Lombardelli; Isabel dos Santos Silva; Alan Ashworth; Julian Peto


Book ID
117290459
Publisher
The Lancet
Year
2005
Tongue
English
Weight
80 KB
Volume
366
Category
Article
ISSN
0140-6736

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The breast cancer low-penetrance allele
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## Abstract Searching for low‐penetrance genes involved in breast cancer susceptibility has been a field of interest in the last few years. Recently, the CHEK 2 gene, involved in DNA damage and replication checkpoints, has been pointed out as a good candidate; moreover, a specific variant in this g