Interaction among substrates, inhibitors and Mn2+ bound to glutamine synthetase as studied by NMR relaxation rate measurements

An NMR study of the interaction between

An NMR study of the interaction between Melanin Free Acid and Mn2+ ions as a model to mimic the enhanced proton relaxation rates in melanotic melanoma

✍ Silvio Aime; Mauro Fasano; Enzo Terreno; Corrado Sarzanini; Edoardo Mentasti 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 626 KB

The interaction of a soluble Melanin Free Acid (MFA) from Sepia melanin with Mn2+ ions is investigated by measuring the proton water relaxation rates. The similarity between MFA and the parent melanin is assessed by means of their high resolution 13C cross polarization magic angle spinning NMR spect