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Inter-Subunit Coordination in Hsp104, a Protein Disaggregase

✍ Scribed by DeSantis, Morgan E.; Leung, Eunice H.; Sweeny, Elizabeth A.; Jackrel, Meredith E.; Cushman-Nick, M.; Neuhaus-Follini, Alexandra; Vashist, Shilpa; Sochor, Matthew A.; Knight, M. Noelle; Shorter, James


Book ID
122332995
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
38 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract **Background:** The [__PSI__^+^] element of the budding yeast is an aggregated form of the translation release factor Sup35 that is propagated and transmitted cytoplasmically in a manner analogous to that of mammalian prions. The N‐terminal of Sup35, necessary for [__PSI__^+^], contains