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Inter-individual variation of several cytochrome P450 2D6 splice variants in human liver

✍ Scribed by Jackie Denson; Yongchun Wu; Wenjian Yang; Jiong Zhang

Book ID
116290219
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
285 KB
Volume
330
Category
Article
ISSN
0006-291X

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## Abstract __Microsomal cytochrome P450 monooxygenases of groups 1–3 are mainly expressed in the liver and play a crucial role in phase 1 reactions of xenobiotic metabolism. The cDNAs encoding human CYP2D6 and human NADPH‐P450 oxidoreductase (CPR) were transformed into the methylotrophic yeast__ P