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Inter- and Intramolecular Hydroamination of Unactivated Alkenes Catalysed by a Combination of Copper and Silver Salts: The Unveiling of a Brønstedt Acid Catalysis

✍ Scribed by Christophe Michon; Florian Medina; Frédéric Capet; Pascal Roussel; Francine Agbossou-Niedercorn


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
390 KB
Volume
352
Category
Article
ISSN
1615-4150

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✦ Synopsis


The combined use of a copper halide, a silver salt and a phosphane ligand was applied for the catalysis of inter-and intramolecular hydroamination of alkenes. The reactions of unactivated olefins with nitrogen substrates were investigated. Mechanistic investigations demonstrated that the cat-alytic system generated a Brønsted acid which appeared to be the prominent catalytic species.