𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inter- and intra-person cytomegalovirus infection in Malawian families

✍ Scribed by Mohammed M. Beyari; T.A. Hodgson; W. Kondowe; E.M. Molyneux; C. Scully; S.R. Porter; C.G. Teo

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
349 KB
Volume
75
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Sequence polymorphisms in the gN and gO genes of cytomegalovirus (CMV) amplified from mouth rinse and urine samples of 19 Malawian patients with Kaposi's sarcoma (KS) and 58 of their first‐degree relatives were investigated. CMV‐DNA was amplified from 41 people (53%) from either the gN or gO region in at least one sample, from 14 people (18%) in both domains in at least one sample, and from 13 (17%) in either domain in both samples. Twenty‐one (51%) were seropositive for human immunodeficiency virus‐1 (HIV). Identical gN sequences were recovered from eight families and non‐identical sequences in six, while identical gO sequences were found in three families and non‐identical sequences in five. Five people, four of whom were children, each carried multitypic gN sequences or gO sequences. The findings are consistent with CMV spread along intra‐ and extra‐household routes, and with multiple intra‐host CMV infection. J. Med. Virol. 75:575–582, 2005. © 2005 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Molecular epidemiology of primary human
Molecular epidemiology of primary human cytomegalovirus infection in pregnant women and their families
✍ Maria Grazia Revello; Giulia Campanini; Antonio Piralla; Milena Furione; Elena P 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB

## Abstract The source of human cytomegalovirus (HCMV) infection was investigated in 29 pregnant women with primary HCMV infection by comparing DNA sequences of UL146, UL144 and a portion of UL55 gene of HCMV strains circulating within each family. Thirteen families were identified in which the pre

Intra and inter-person sources of variab
Intra and inter-person sources of variability in fat intake in a feeding trial of 14 men
✍ J. R. Hebert; J. Y. Chen Backlund; A. Engle; J. Barone; K. Biener 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 541 KB

An impediment to analyzing the effect of nutritional factors on biologic processes or health status in human populations arises from the relatively small dietary differences that exist between individuals in relation to large periodic fluctuations in dietary intake and the imprecision with which die