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Inter- and intra-individual variation in L-dopa pharmacokinetics in the treatment of Parkinson's disease

✍ Scribed by Masahiro Nomoto; Noriko Nishikawa; Masahiro Nagai; Hayato Yabe; Akiko Nakatsuka; Hiroyoko Moritoyo; Takashi Moritoyo; Madoka Kubo


Book ID
117753214
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
562 KB
Volume
15
Category
Article
ISSN
1353-8020

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We compared the neuropsychological performance of patients with Parkinson's disease who were young at onset of the disease (mean age, 41.4 years) and had received prolonged L-dopa treatment (mean, 52.1 months) with nontreated patients of the same age. A similar comparison was made for patients who w