Having demonstrated in a laboratory model that the neurotoxicity of CNS irradiation can be ameliorated with pre-irradiation methotrexate, we retrospectively compared two methods of CNS prophylaxis in childhood acute lymphoblastic leukemia which differed only in the timing of intrathecal methotrexate
Intellectual function in long-term survivors of childhood acute lymphoblastic leukemia
β Scribed by E. Ladavas; G. Missiroli; P. Rosito; L. Serra; V. Vecchi
- Publisher
- Springer Milan
- Year
- 1985
- Tongue
- English
- Weight
- 371 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1590-1874
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## Abstract There have been varying frequencies cited for the occurrence of abnormal brain CT scans in Jeukemic patients and confiding evidence about the significance of these abnormalities and their relationship to sanctuary therapy. Our study of CT brain scans in 26 long survivors of acute lympho
## Abstract ## BACKGROUND The objective of the current study was to determine whether therapy for childhood acute lymphoblastic leukemia (ALL) results in longβlasting neurologic signs or electrophysiologic injuries within the motor tracts. ## METHODS Twentyβseven children who were treated for AL