Integrity of the blood-CSF barrier in dementia of Alzheimer type: CSF/serum ratios of albumin and IgG
✍ Scribed by L. Frölich; J. Kornhuber; R. Ihl; J. Fritze; K. Maurer; P. Riederer
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 498 KB
- Volume
- 240
- Category
- Article
- ISSN
- 1433-8491
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The monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in lumbar cerebrospinal fluid (CSF) were measured in 15 patients with dementia of the Alzheimer type (DAT) and 48 controls by means of a sensitive liquid chromotagraphic method. Relative to a large group of con
## Abstract Permeability‐surface area products (PAs) of the blood‐nerve barrier (BNB) and blood‐brain barrier (BBB) to ^125^I‐labeled native bovine serum albumin (nBSA, pI ∼︁4), and to 2 cationized albumins (cBSA) of differing pI (pI ∼︁ 8 and 11), were quantitatively determined in awake rats, using