Integrins as therapeutic targets
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Simon L. Goodman; Martin Picard
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Article
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2012
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Elsevier Science
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English
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Integrins are a large family of molecules that are central regulators in multicellular biology. They orchestrate cell-cell and cell-extracellular matrix (ECM) adhesive interactions from embryonic development to mature tissue function. Diverse human pathologies involve integrin adhesion, including th