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Integrin-Mediated Activation of Focal Adhesion Kinase Is Required for Signaling to Jun NH2-Terminal Kinase and Progression through the G1 Phase of the Cell Cycle

✍ Scribed by Maja Oktay, Kishore K. Wary, Michael Dans, Raymond B. Birge and Filippo G. Giancotti


Book ID
124805028
Publisher
Rockefeller University Press.
Year
1999
Tongue
English
Weight
841 KB
Volume
145
Category
Article
ISSN
0021-9525

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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) δ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCδ has a negative effect on cell proliferation. However, the mode of PKCδ activation, the cell cycle stage requ