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Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling

✍ Scribed by Shoukat Dedhar; Benjamin Williams; Gregory Hannigan


Book ID
114323619
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
348 KB
Volume
9
Category
Article
ISSN
0962-8924

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## Abstract Bone resorption requires the adhesion of osteoclasts to extracellular matrix (ECM) components, a process mediated by the Ξ±~v~Ξ²~3~ integrin. Following engagement with the ECM, integrin receptors signal via multiple downstream effectors, including the integrin‐linked kinase (ILK). In orde