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Integrin cytoplasmic domain_ small face but big player

โœ Scribed by J. Qin


Book ID
116729349
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
56 KB
Volume
25
Category
Article
ISSN
0945-053X

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โœ Deirdre Crommie; Martin E. Hemler ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 198 KB

The anti-integrin โค1 MAb 15/7 sometimes may be a reporter of integrin activation or ligand occupancy. However, certain โค1 tail deletions eliminate ligand binding despite inducing maximal constitutive 15/7 expression : J Biol Chem 271:16580-16585]. Here we describe โค1 tail mutations (e.g., double poi