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Integrin- and Cadherin-Mediated Induction of the Matrix Metalloprotease Matrilysin in Cocultures of Malignant Oral Squamous Cell Carcinoma Cells and Dermal Fibroblasts

โœ Scribed by Elisabeth L. Bair; Chad P. Massey; Nhan L. Tran; Alexander H. Borchers; Ronald L. Heimark; Anne E. Cress; G.Tim Bowden


Book ID
115604120
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
103 KB
Volume
270
Category
Article
ISSN
0014-4827

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In addition to their role in maintenance of tissue integrity, cell adhesion molecules regulate the growth and differentiation of stratified squamous epithelia. Reduced expression of E-cadherin and the 2 1 , 3 1 and 6 4 integrins is already reported to correlate with poor histological differentiation