Integration of human T-cell leukemia virus type 1 in genes of leukemia cells of patients with adult T-cell leukemia
โ Scribed by Shuji Hanai; Takayuki Nitta; Momoko Shoda; Masakazu Tanaka; Naomi Iso; Izuru Mizoguchi; Shinji Yashiki; Shunro Sonoda; Yuichi Hasegawa; Toshiro Nagasawa; Masanao Miwa
- Book ID
- 108582412
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 390 KB
- Volume
- 95
- Category
- Article
- ISSN
- 1347-9032
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It is known that the expression levels of intercellular adhesion molecule-1 (ICAM-1) in adult T cell leukemia(ATL) cells are high, whereas those in T-lymphoid cells are not. In order to investigate the factors that influence the induction of ICAM-1 molecules , Northern blot analysis to measure the e
Human T-cell leukemia virus type I (HTLV-I) is etiologically associated with adult T-cell leukemia/lymphoma (ATL). We cloned and sequenced host DNA adjacent to the long terminal repeats of HTLV-I from uncultured leukemic cells of 4 ATL patients. The region flanking the provirus was generally A/Trich