Integration of hepatitis B virus DNA and hepatocellular carcinoma
β Scribed by SHOICHI TAKAHASHI; KAZUAKI CHAYAMA
- Book ID
- 108950395
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 56 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0815-9319
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To investigate the relationship between hepatocarcinogenesis and integration of hepatitis B virus (HBV) DNA in the cellular DNA of the liver, we studied the integration of HBV DNA in various noncancerous regions of the liver from 31 patients using Southern blot analysis. Of 13 patients without hepat
## Abstract The DNA of tumor tissue K1 obtained at autopsy from a case of hepatocellular carcinoma (HCC) in a 9βyearβold boy contained integrated hepatitis B virus (HBV) DNA at a single site in the chromosome (case 2, Chang et al.: Hepatology 13:316β320, 1991). To characterize further the integrate
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