## Abstract Amplification of a defined chromosome segment on the short arm of chromosome 7 has frequently been reported in glioblastoma multiforme (GBM), where it is generally assumed that it is the result of over expression of the epidermal growth factor receptor (__EGFR__) gene that provides the
✦ LIBER ✦
Integration of Global Spectral Karyotyping, CGH Arrays, and Expression Arrays Reveals Important Genes in the Pathogenesis of Glioblastoma Multiforme
✍ Scribed by Leone, Paola E.; González, M. Belén; Elosua, Carolina; Gómez-Moreta, Juan A.; Lumbreras, Eva; Robledo, Cristina; Santos-Briz, Angel; Valero, José Maria; Guardia, Rafael Díaz; Gutiérrez, Norma C.; Hernández, Jesús M.; García, Juan L.
- Book ID
- 115031705
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 431 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1068-9265
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## Background and objectives: Several molecular biology techniques are utilized to study changes in gene expression during the genesis of human tumors. our objective was to identify genes that showed altered expression between normal brain tissue (nbt) and glioblastoma multiforme tumor tissue (gmtt