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Integration of Genomic and Genetic Approaches Implicates IREB2 as a COPD Susceptibility Gene

✍ Scribed by Dawn L. DeMeo; Thomas Mariani; Soumyaroop Bhattacharya; Sorachai Srisuma; Christoph Lange; Augusto Litonjua; Raphael Bueno; Sreekumar G. Pillai; David A. Lomas; David Sparrow; Steven D. Shapiro; Gerard J. Criner; Hong P. Kim; Zhihua Chen; Augustine M.K. Choi; John Reilly; Edwin K. Silverman


Book ID
113422698
Publisher
American Society of Human Genetics
Year
2009
Tongue
English
Weight
861 KB
Volume
85
Category
Article
ISSN
0002-9297

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We performed global RNA transcript analysis and comprehensive gene group analysis of peripheral blood leukocyte (PBL) RNA from two groups of matched sib-pairs that were discordant for either schizophrenia (n = 33 sib-pairs) or bipolar disorder (n = 5 sib-pairs). The pairs chosen for these analyses w