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Integrating computational and mixture-based screening of combinatorial libraries

✍ Scribed by Austin B. Yongye; Clemencia Pinilla; Jose L. Medina-Franco; Marc A. Giulianotti; Colette T. Dooley; Jon R. Appel; Adel Nefzi; Thomas Scior; Richard A. Houghten; Karina Martínez-Mayorga

Book ID
106240396
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
450 KB
Volume
17
Category
Article
ISSN
1610-2940

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Computational screening of combinatorial
Computational screening of combinatorial libraries
✍ Qiang Zheng; Donald J. Kyle 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 734 KB

We first review existing computational methods with an intrinsic combinatorial feature, then describe a new computational method for screening combinatorial libraries using a recently developed multicopy sampling technique. The new method differs from the existing ones in that it can be used to scre