## Abstract The tumor suppressor gene __maspin__ has been reported to inhibit the invasiveness and motility of breast cancer cells. It has been reported that maspin is expressed in normal human mammary epithelial cells but is downregulated during cancer progression, and that p53 could induce maspin
Integrated gene expression profile predicts prognosis of breast cancer patients
β Scribed by Lian-Fang Li; Xiao-Jing Xu; Ying Zhao; Zhe-Bing Liu; Zhen-Zhou Shen; Wei-Rong Jin; Zhi-Ming Shao
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 366 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0167-6806
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## Abstract The prognostic significance of __BRCA2__ mRNA levels in tumor tissues was studied in sporadic breast cancer patients. __BRCA2__ mRNA levels were determined by realβtime PCR. Histologic grade III tumors showed significantly (__p__ = 0.001) higher __BRCA2__ mRNA levels (0.828 Β± 0.102 __BR
## Abstract Promising results for prediction of outcome in breast cancer have been obtained by genome wide gene expression profiling. Some studies have suggested that an extensive overtreatment of breast cancer patients might be reduced by risk assessment with gene expression profiling. A patient g