Integrated Chemical Process: An Extremely Concise Synthesis of Vitamin A

✍ Scribed by Dr. Akihiro Orita; Yasuo Yamashita; Akiji Toh; Prof. Dr. Junzo Otera

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 305 KB
• Volume: 36
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.199707791

✦ Synopsis

otera!o dac.ous.ac.jp Scheme 1. Stepwise synthesis of vitamin A (5). A) Dihydropyran (R = tetrahydropyranyl), ethylvinyl etherlp-toluenesulfonic acid (R = 1-ethoxyethyl) or (MeO),CH,/P,O,) (R = MOM) in CH,CI, or neat. B) tBuOK or MeOK in cyclohexane.