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Integrated approach to the management of patients with advanced germ cell tumors of the testis

✍ Scribed by Dr. R. Ravi; R. Ranga Rao; V. Shanta

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
503 KB
Volume
55
Category
Article
ISSN
0022-4790

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✦ Synopsis

Abstract

Between 1985 and 1991, 63 patients with disseminated germ cell tumors of the testis were treated with initial cisplatin based combination chemotherapy. Complete response was seen in 38% of patients. Adjunctive surgical resection of residual disease was carried out in 26 patients (41%), including the use of intraoperative radiation therapy in two patients with seminoma. Furthermore, two other patients with seminoma and residual mass underwentretroperitoneal irradiation. Salvage chemotherapy was administered to five patients with progressive disease, and only one of these could be salvaged with adjunctive surgery. A disease‐free state was achieved in 75% of patients at a mean follow‐up period of 30 months. Β© Wiley‐Liss, Inc.

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Autopsy findings in 154 patients with ge
Autopsy findings in 154 patients with germ cell tumors of the testis
✍ Jacques J. Bredael; Davor Vugrin; Willet F. Whitmore Jr. πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 355 KB πŸ‘ 3 views

Autopsy findings are reviewed in 154 patients treated for germ cell tumors of the testis. OF the patients with apparently pure seminoma, 44% had autopsy evidence of nonseminomatous metastases. For all tumor types, the most common sites of distant metastasis were lung (89%), liver (73%), brain (31%),