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Integral Membrane Proteins in Nanodiscs Can Be Studied by Solution NMR Spectroscopy

✍ Scribed by Glück, Julian M.; Wittlich, Marc; Feuerstein, Sophie; Hoffmann, Silke; Willbold, Dieter; Koenig, Bernd W.

Book ID
118250741
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
450 KB
Volume
131
Category
Article
ISSN
0002-7863

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Three different conformations of proline rings in a protein in solution, Up, Down and Twist, have been distinguished, and stereospecific assignments of the pyrrolidine beta-, gamma- and delta-hydrogens have been made on the basis of 1H-1H vicinal coupling constant patterns and intraresidue NOEs. For