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Intact working memory in the absence of forebrain neuronal glycine transporter 1

✍ Scribed by Sylvain Dubroqua; Lucas Serrano; Detlev Boison; Joram Feldon; Pascual A. Gargiulo; Benjamin K. Yee


Book ID
116286749
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
554 KB
Volume
230
Category
Article
ISSN
0166-4328

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Two membrane-localized transporter proteins (GLYT1 and GLYT2) are responsible for removal of extracellular glycine in the mammalian CNS. Whereas GLYT1 seems to be expressed mainly in glial cells, GLYT2 is neuronal. The highest concentrations of both transporters are found in glycinergic areas of the