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Insulin treatment (hormonal imprinting) increases the insulin production of the unicellular Tetrahymena long term. Is there a simultaneous formation of hormone receptor and hormone?

✍ Scribed by G. Csaba; P. Kovács


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
172 KB
Volume
19
Category
Article
ISSN
1065-6995

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✦ Synopsis


Abstract

Insulin treatment of Tetrahymena pyriformis resulted in a long‐lasting increase in the insulin content of the cells. After about 200 generations, insulin levels significantly higher than in the control were demonstrated by using a quantitative immunocytochemical method. Although the insulin content fluctuated from day to day, it was always higher in the insulin pre‐treated (imprinted) cells than in the controls. The results emphasise the simultaneous stimulation of hormone and receptor formation by hormonal imprinting.