Insulin resistance was assessed after an intravenous infusion of adrenaline (50 ng.kg-1.min-1) or saline (control study) given between 08.00 and 08.30 hours in nine patients with Type 1 (insulin-dependent) diabetes mellitus. The blood glucose level during a somatostatin (100 micrograms/h)-insulin (0
Insulin resistance in Type 1 (insulin-dependent) diabetes following hypoglycaemia — evidence for the importance of β-adrenergic stimulation
✍ Scribed by S. Attvall; J. Fowelin; H. von Schenck; I. Lager; U. Smith
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 717 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0012-186X
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It has long been assumed that replacement of insulin in insulin-deficient diabetic patients will normalise glucose utilization. In this study, glucose utilization was measured in nine long-standing, poorly controlled diabetic patients and five control subjects, matched for age (33 +/- 3 versus 33 +/
We studied prospectively 49 non-diabetic identical twins of recently-diagnosed Type 1 (insulin-dependent) diabetic patients for up to 24 years (median 9 years). During this time 15 developed Type 1 diabetes. Actuarial analysis indicates that by 12 years 34% of the twins will have developed Type 1 di