Insulin regulates protein synthesis rate in leukocytes from young and elderly healthy humans
✍ Scribed by Stéphane Walrand; Christelle Guillet; Pierre Gachon; Christophe Giraudet; Paulette Rousset; Marie-Paule Vasson; Yves Boirie
- Book ID
- 113545107
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 207 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0261-5614
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Cultured human retinal pigment epithelial cells (RPE) secrete insulin‐like growth factor binding proteins (IGFBPs), a family of polypeptides which modulate the actions of the insulin‐like growth factors. RPE cells secrete two IGFBPs with Mr estimates of 34,000 and 46,000, respectively.
Insulin-like growth factor-1, IGF-1, is believed to be an important anabolic modulator of cartilage metabolism whose action is mediated by high affinity cell surface receptors and bioactivity and bioavailability regulated, in part, by IGF-1 binding proteins (IGFBPs). Prostaglandin E 2 (PGE 2 ) stimu