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Insulin receptors on chinese hamster ovary (CHO) cells: Altered insulin binding to glycosylation mutants

✍ Scribed by Judith Podskalny; Aidan McElduff; Phillip Gorden

Book ID
117056637
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
225 KB
Volume
125
Category
Article
ISSN
0006-291X

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## Abstract From the Chinese hamster ovary (CHO) cell, genetic variants (Mon^R^–31 and Mon^R^–32) relatively resistant to monensin, an ionophoric antibiotic, have been isolated. Growth of both Mon^R^‐31 and Mon^R^‐32 clones required higher doses of serum than CHO. Addition of insulin to media conta