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Insulin receptor tyrosine kinase activity and substrate 1 (IRS-1) expression in human myometrium and leiomyoma

✍ Scribed by Rafael B. Orcy; Ilma Brum; Roselis S.M. da Silva; Luiz C.R. Kucharski; Helena v. E. Corleta; Edison Capp

Book ID: 116434149
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 139 KB
Volume: 123
Category: Article
ISSN: 0301-2115
DOI: 10.1016/j.ejogrb.2005.02.025

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## Abstract Insulin receptor substrate (IRS) proteins play a central role in insulin signaling. Previously we have demonstrated that insulin is essential for normal skin development and function. In the present study we investigated the involvement of the IRS‐1 and IRS‐2 proteins in skin physiology