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Insulin receptor-deficient cells as a new tool for dissecting complex interplay in insulin and insulin-like growth factors

✍ Scribed by B Lamothe; A Baudry; C.T Christoffersen; P De Meyts; J Jami; D Bucchini; R.L Joshi


Book ID
117109054
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
134 KB
Volume
426
Category
Article
ISSN
0014-5793

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## Abstract The insulin‐like growth factor (IGF) system plays an important role in cell proliferation and survival. However, more recently, a small number of studies have shown that IGFs induce apoptosis in some cells. Our initial studies showed this occurred in LIM 1215 colon cancer cells but not