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Insulin receptor-associated protein tyrosine phosphatase(s): Role in insulin action

✍ Scribed by Paul G. Drake; Barry I. Posner

Book ID
110241522
Publisher
Springer
Year
1998
Tongue
English
Weight
320 KB
Volume
182
Category
Article
ISSN
0300-8177

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Protein-tyrosine phosphatases (PTPases) play an important role in the regulation of insulin action by dephosphorylating the active (autophosphorylated) form of the insulin receptor and attenuating its tyrosine kinase activity. PTPases can also modulate post-receptor signalling by catalyzing the deph