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Insulin modulation of intracellular free magnesium in heart: involvement of protein kinase C

✍ Scribed by Tetsuya Amano; Tatsuaki Matsubara; Junji Watanabe; Shinsuke Nakayama; Nigishi Hotta


Book ID
110005039
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
180 KB
Volume
130
Category
Article
ISSN
0007-1188

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The insulin modulation of Na-H antiport in rat hepatocytes was studied using the fluorescent, pH-sensitive intracellular probe, 2',7' bis (carboxyethyl)-5(6)-car- boxyfluorescein (BCECF). Our data show that insulin stimulates the Na-H antiport. The dose-response of insulin effect shows a behavior ty