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Insulin-like growth factor signalling pathways in rat hepatic stellate cells: Effects on DNA synthesis and hepatocyte growth factor production

✍ Scribed by S. Skrtic; K. Blad; A.M. Gressner; J.-O. Jansson


Book ID
117735324
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
81 KB
Volume
9
Category
Article
ISSN
1096-6374

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Insulin and insulin-like growth factor-1
✍ Gianluca Svegliati-Baroni; Francesco Ridolfi; Antonio Di Sario; Alessandro Casin πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 323 KB

Insulin and insulin-like growth factor (IGF-1) are mitogenic for fibroblasts and smooth muscle cells. IGF-1 increases in inflamed and fibrotic tissues and induces proliferation of rat hepatic stellate cells (HSC). This study evaluates the potential roles of these hormones in the development of liver