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Insulin-like growth factor signaling regulates cell survival and cell cycle progression in developing zebrafish embryos

✍ Scribed by Peter J. Schlueter; Gang Peng; Yun Li; Monte Westerfield; Cunming Duan


Book ID
116975700
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
62 KB
Volume
295
Category
Article
ISSN
0012-1606

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## Abstract Neuroblastoma is a common pediatric malignancy that metastasizes to the liver, bone, and other organs. Children with metastatic disease have a less than 50% chance of survival with current treatments. Insulin‐like growth factors (IGFs) stimulate neuroblastoma growth, survival, and motil